Azithromycin
Catalog Number : 8390155
description
Azithromycin is an acid-stable macrolide antibiotic that inhibits protein synthesis by binding to the 50S subunit of the bacterial ribosome. It is reported to inhibit autophagy. It is currently being researched as a potential treatment for COVID-19.
Additional Information
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Applications:
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FA
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Synonyms:
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Azitrocin, CP-62993, Sumamed, Zithromax
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Formulation:
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Crystalline solid
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Chemical Name:
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(2R,3S,4R,5R,8R,10R,11R,12S,13S,14R)-11-[(2S,3R,4S,6R)-4-(dimethylamino)-3-hydroxy-6-methyloxan-2-yl]oxy-2-ethyl-3,4,10-trihydroxy-13-[(2R,4R,5S,6S)-5-hydroxy-4-methoxy-4,6-dimethyloxan-2-yl]oxy-3,5,6,8,10,12,14-heptamethyl-1-oxa-6-azacyclopentadecan-15-one
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Molecular Formula:
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C38H72N2O12 |
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Molecular Weight: |
749.0
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CAS Number
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83905-01-5
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Purity:
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98%
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Storage Conditions:
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Product should be kept at -20°C.
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References:
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Peters, D. H., Friedel, H. A., & McTavish, D. (1992). Azithromycin. Drugs, 44(5), 750-799. Qiao, X., Wang, X., Shang, Y., Li, Y., & Chen, S. Z. (2018). Azithromycin enhances anticancer activity of TRAIL by inhibiting autophagy and up-regulating the protein levels of DR4/5 in colon cancer cells in vitro and in vivo. Cancer Communications, 38(1), 43. Gautret, P., Lagier, J. C., Parola, P., Meddeb, L., Mailhe, M., Doudier, B., ... & Honoré, S. (2020). Hydroxychloroquine and azithromycin as a treatment of COVID-19: results of an open-label non-randomized clinical trial. International Journal of Antimicrobial Agents, 105949. |